CareJules Homecare Essential Guide

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Essential Guide to Home Care

Everything you need to know about care at home.

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Essential Guide to Home Care

CareJules Homecare Essential Guide

Innovative Treatments to Reverse Alzheimer's, Dementia & Memory Loss

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Essential Guide to Home Care

Discover the Procedures to Slow Down & even Reverse the Symptoms

Even though there currently isn't a cure for Alzheimer's and dementia, there are new promising therapies breaking through. Some protocols can reverse 9 out of 10 patients symptoms - With subsequent tests clearing their initial diagnoses.

Clearly, there are changes we can do and make to repair and regenerate our brains. We can strengthen our brains to resist disease.

In contrast, our current medication offers very little help. The NHS dementia guide says...

Most of the medications available are used to treat Alzheimer's disease as this is the most common form of dementia. They can help to temporarily reduce symptoms.1

In fact, drug treatments offer little hope. Alzheimer's medicines can temporarily lighten symptoms, and maybe slow down the disease progression. But a short-term gain may come with side-effects, such as a loss of appetite, nausea, vomiting and diarrhoea, muscle cramps, headaches, dizziness, fatigue, insomnia, raised blood pressure, constipation and epileptic seizures to name just a few.2,3,4,5,6Are they worth the risk?

Considering the risk and reward...

...there are Safe Developed Protocols to Repair & Regenerate the Brain


The Bredesen Protocol

"The first proven method to reverse the effects of early Alzheimer's disease"... The Bredesen Protocol shows us how to rebalance using lifestyle modifications... With a multi-step program designed to find all of the causes and begin to fix them. As Dr Bredesen says, a single drug would have to address every problem, many more than any drug has done in our history.

Fortunately, there are changes you can make to your loved one's lifestyle that will help them revive their brain. With a 36-point therapeutic program, Metabolic Enhancement for Neurodegeneration (MEND), "Patients who had to discontinue work were able to return to work, and those struggling at work were able to improve their performance. The patients, their spouses, and their co‐workers all reported clear improvements."

The great news is, even though none of the participants was able to be 100% compliant, 90% got amazing results. By making major changes to their lifestyle and doing their very best to stick with it for 5 to 24 months, these patients met the criteria for Alzheimer’s disease or mild cognitive impairment (MCI) before the treatment and then went on to pass the tests while following the program.

By Following the Treatment, most had Returned to the Normal Cognitive Testing Range

Because Dr Bredesen's Alzheimer's and dementia treatment is groundbreaking, the results of the study couldn't be seen as scientific evidence. In fact, he noted that a more extensive, controlled clinical trial is needed. Nevertheless, Dr Bredesen has followed up the first study with another to further prove his protocol has merit.7,8

In one of the cases, a patient with a demanding job was forgetting her way home. But with a personalised therapy developed by Dr Bredesen's extensive testing to determine what was affecting her brain’s network, she returned to normal. Now she's living without the signs of dementia.

In order to better understand how Dr Bredesen's Alzheimer's and dementia MEND program works, he explains it like this:

The existing Alzheimer’s drugs affect a single target, but Alzheimer’s disease is more complex. Imagine having a roof with 36 holes in it, and your drug patched one hole very well. The drug may have worked, and a single hole may have been fixed, but you still have 35 other leaks, and so the underlying process may not be affected much.

The Bredesen Protocol includes:

  • Eating whole foods. Eliminate simple carbohydrates, gluten, grains and processed foods from the diet. Replace them with more vegetables, fruits and wild/non-farmed fish.

  • Increase antioxidants. An antioxidant-rich diet may help to improve cognitive functioning. Add more antioxidant-rich foods like blueberries and blackberries. Eat one Brazil nut daily for selenium. Supplement with 400 mg of vitamin E (mixed tocopherols and tocotrienols), 500-1,000 mg of vitamin C, and 200 mg of alpha lipoic acid.

  • Supplement Diet. Daily intake of curcumin, ashwagandha, vitamin D3, B12 (methylcobalamin), K2, fish oil and coenzyme Q10. Curcumin is an active component of turmeric. It has a natural anti-inflammatory effect and is linked to a reduction of amyloid beta (Ab) peptides. The typical dosage recommended is 400-500 mg of curcumin, two to three times daily with an absorption-enhancer such as piperine from black pepper. Ashwagandha may provide neuroprotection and improve memory formation. The optimal dose is 6,000mg a day, usually divided into three (2,000mg) doses. Vitamin D3 increases cognition. The lowest effective dose range is 1,000-2,000IU. Higher daily doses are 20-80IU per kg of body weight. Vitamin B12 affects cognitive function such as memory, focus, attention, and intelligence, and overall brain health. Most of the population are B12 deficient, therefore, it's often recommended to take 1,000mcg (1mg). Brain concentrations of Vitamin K2 decline with age, so supplementing with the minimum effective dose of 1,500mcg for MK-4 or 90-360mcg for MK-7, MK-8, and MK-9 may be beneficial. A 6g dose of fish oil, spread over the course of a day, may be effective at reducing the rate of cognitive decline. Coenzyme Q10 might protect cognition during advanced age. The standard dose for CoQ10 is generally 90mg to 200mg, taken once-a-day with a meal. However, a higher dose is not always best.

  • The Gut-Brain connection. Probiotics & prebiotics can boost the immune system and help to reduce inflammation. Therefore, add probiotic-rich foods like plain Greek yoghurt, kombucha, kefir, and fermented foods like miso and sauerkraut.

  • Build new brain junctions. By increasing citicoline and DHA (an omega-3 fatty acid), new brain synapses can be formed. To improve verbal memory, supplement with 1,000 to 2,000 mg citicoline daily. Plus, a higher dietary intake of DHA (900 mg) from oily fish like salmon and sardines, krill, and microalgae is associated with a decreased risk of developing Alzheimer's disease.

  • Reduce stress. High levels of stress risk factors are linked to Alzheimer's. Therefore, they may need lowering. To reduce cortisol and CRF (corticotropin-releasing factor) try including yoga, meditation twice a day, music, and taking regular walks.

  • Sleep. Get seven to eight hours per night. Address any sleep issues such as sleep apnea and insomnia. If required, supplement with melatonin. According to some research, melatonin might protect against neurodegenerative disorders. By taking 2.5 mg to 3 mg of melatonin before bedtime, it can reduce confusion and restlessness some dementia patients experience.

  • Improve oral hygiene. Keep the mouth clean and free of disease because bad mouth bacteria have been found in the brains of dementia patients. Regularly brushing the teeth and cleaning between the teeth with an electric flosser and electric toothbrush may help.

  • Balance hormones. Recent studies show hormones may keep cells from ageing quickly, thereby lowering Alzheimer's risk. So optimise fT3, fT4, E2, T, progesterone, pregnenolone, and cortisol with Bioidentical hormones.

  • Restrict feasting by fasting. Stop eating for a minimum of 12 hours between dinner and breakfast, and for a minimum of three hours between dinner and bedtime. This will begin ketogenesis, reduce insulin levels, and reduce amyloid beta (Ab), the amino acids linked to Alzheimer's disease. These amino acids are the main parts of the amyloid plaques found in the brain.

  • Move! Because research shows exercise may improve cognition, memory, and slow down mental decline. Therefore, exercise for a minimum of 30 minutes, four to six days per week.

  • Cognitive enhancement. Bacopa monnieri can improve the total memory score and maximum improvement was seen in logical memory and paired associate learning. Given doses range from 250–500 mg once or twice a day. MgT (magnesium-L-threonate) may prevent the loss of synapses between neurons and reduce the beta-amyloid plaques and prevent memory decline according to the latest study in Alzheimer's mice. Human studies are underway with the recommended dose of two grams per day. One gram in the afternoon and another in the evening.

  • Optimize mitochondria. The most prominent role of mitochondria is to produce the energy of the cell, ATP. We know mitochondria are dysfunctional in the brains of dementia patients. So by improving mitochondrial function with CoQ or ubiquinol, α-lipoic acid, PQQ, NAC, ALCAR, Se, Zn, resveratrol, ascorbate, and thiamine, research suggests healthy mitochondria help in the fight against the disease. CoQ10 is generally 90mg to 200mg, taken once-a-day with a meal. Clinical trials with α-lipoic acid on Alzheimer's patients have used doses from 600 to 900 mg/day. While the optimal Pyrroloquinoline quinone (PQQ) daily dose is currently unknown, most dietary supplements contain 20-40mg. N-Acetylcysteine (NAC) may have neuroprotective potential. 800mg-1,800mg is usually recommended as a medical treatment. The brain booster, Acetyl-L-Carnitine (ALCAR), increases mitochondrial capacity from supplementing 630-2,500mg daily. Alzheimer's Dementia patients show significantly lower Selenium (Se) levels. To alleviate this deficiency, patients should aim for 200-300ug daily. While zinc (Zn) concentrations should be monitored because low zinc levels are not good for mitochondrial function and may increase dementia and excess zinc in the brain may contribute to Alzheimer's Dementia. Daily Zinc should be provided from the diet, however, a low dosage of 5-10mg may be prescribed. While the high dosage of 25-45mg might be needed to reverse a deficiency. Also, short-term super-loading up to 100mg zinc a day is safe. Resveratrol supplementation seems to increase mitochondrial biogenesis. As little as 5mg per day could make an impact on an unhealthy person. Whereas, 250-500mg daily is administered to otherwise healthy people. Ascorbate's (Vitamin C) ability to regulate the production of free radicals may be relevant. While the Recommended Daily Intake (RDI) of vitamin C is 100-200mg, you'd likely need a much higher dose, over 2,000mg per day to benefit. Thiamine (Vitamin B1) restoration may increase available energy to the mitochondria. A deficiency may be supplemented daily with 100-300mg.

  • Increase focus. Pantothenic acid (Vitamin B5)is required to make acetylcholine (ACh). Sufficient levels can boost focus. With an adequate daily intake of 5 mg, sometimes higher levels of 7 mg, Vitamin B5 should enhance alertness and cognition.

  • MCT effects. For some dementia sufferers, the brain has become glucose resistant, therefore, an alternative fuel is required. Coconut oil or Axona contains medium-chain triglycerides that provide ketones as an alternative fuel for the brain. Supplementing with MCT's may help reverse Alzheimer's and dementia.


The Amen Healing Protocol

Once academics believed that the brain could not regenerate. No new cells or neurons. However, the discovery that brain cells and neurons can, in fact, form and restore, changed our approach to brain diseases.

With Dr Daniel Amen's experience of more than 70,000 brain scans on patients, he has moulded an approach to reverse brain damage. This procedure has lead to research on former NFL players. Which came not long after the controversial "Game Brain" story where specialists discovered concussions in pro football players can lead to dementia. Dr Amen's study proves cognitive and cerebral blood flow improvements are possible.9

Nevertheless, some suggest we are living longer and that's why more and more people are developing Alzheimer's and dementia. However, Dr Amen is not one to subscribe to this logic. He says "that in spite of the natural process of ageing, you actually have a choice in how fast your brain ages." He goes on to argue the case for lifestyle making a greater impact. Our behaviours and habits can speed up or slow down the rate of our brains decline. By being mentally and physically active, nourishing our bodies while avoiding harmful habits this can help us sustain brain health and prevent dementia.

Due to this point of view, and science shows us that dementia starts in the brain decades before symptoms appear, we would be wise to develop a healthful lifestyle right now. In his book Change Your Brain Change Your Life, Dr Amen demonstrates a program to reverse diseases of the brain.

The Amen Clinic Program to Regenerate the Brain consists of:

  • Brain-healthy foods - Lots of nutritious and colourful fruits and vegetables and nuts. Organic, free-range and grass-fed, protein. Whole grains and seeds. Healthy fats like olive oil, avocado oil, and coconut oil. Herbs and spices. And plenty of water.

  • New learning - Exercise the brain in as many ways as possible. Try language games, learning a new musical instrument, maths games, map reading, crossword puzzles, memory games... Anything you're not used to or good at.

  • Exercise - Walking with short intense bursts, strength training, mind and body exercise like yoga and tai chi, coordination activities such as hockey, football, tennis, and dancing.

  • Relaxation techniques - Relieving stress is essential. Try deep breathing, meditation, guided imagery, socialising.

  • Healthy blood vessels - Avoid stress, caffeine and nicotine. Get great sleep. Take ginkgo biloba and omega 3 fatty acids.

  • Anti-inflammatory - Regularly eat fish, nuts, broccoli, avocados, cacao, curcumin, rosemary and garlic. Drink green tea.

  • Enhance the Brain - Take supplements to aid the brain. Omega 3; with extremely high doses of fish oil, the brain may be able to heal. Vitamin B6; a deficiency might contribute to cognitive impairment and dementia. The typical dose for a deficiency is 2.5-25 mg daily for three weeks, then 1.5-2.5 mg per day. Vitamin B12; it is common to be deficient which affects memory, focus, attention, intelligence, and overall brain health. Often, the recommended dose is 1mg of B12 (methylcobalamin). Folate/L-methylfolate; supplementation may improve cognitive function. Standard dosages are 400 mcg folate or 7.5-15mg L-methylfolate a day. Vitamin C; regulating free radicals might be important for brain function. A high dose of over 2,000mg per day could be beneficial. Vitamin D3; to increase cognition take a minimum of 1,000-2,000IU. Higher daily doses of 20-80IU per kg of body weight could prove best. Ginkgo biloba; the most common herb for brain function and health. Take 40-120mg, three times a day. Huperzine-A; a cognitive enhancer that improves cognition in vascular dementia patients. Daily supplementing between 50-200mcg and cycling 2-4 weeks with huperzine-A is often recommended because it can remain in the body for some time. Vinpocetine; used as a cognitive protective and anti-ageing supplement. Vinpocetine may enhance blood flow, provide anti-inflammatory effects and is used to treat cognitive decline. Take 15-60mg daily and divide into three doses with meals. Choline; studies suggest clinical usefulness for symptoms of Alzheimer's dementia. Choline is known to be a cognitive booster. 1-2g is typically used split into 3 daily doses. Acetyl-L-Carnitine (ALCAR); supplementing with 630-2,500mg daily boosts the brain by increasing mitochondrial capacity. Alpha-lipoic acid; an anti-ageing compound. It can reverse some of the ageing oxidant damage. The standard dose is between 300-600mg. N-acetyl-cysteine (NAC); supplementation increases neural glutathione concentrations in cells. Take 200-400mg 1-3 times a day. Coenzyme Q10; the elderly might sustain cognition with 90mg to 200mg of CoQ10. Take once-a-day with a meal. Phosphatidylserine (PS); high amounts are found in the brain where it contributes to cognitive function. Generally, 100mg is taken 3 times a day.


The Power of Quality Nutrition

Nourishment is important. It might just be one of the most significant changes you can make to your loved one's lifestyle.

While there are mixed opinions surrounding nutrition, in general, there are ingredients you can add to your relative's diet that might begin to reverse Alzheimer's and dementia.

Nevertheless, most of the nutritional advice for Alzheimer's and dementia patients is standard guidance... "a balanced diet with fruit and veg, whole grains, low-fat dairy, and lean protein foods. And limit salt, sugar, and saturated fat." In fact, the main focus from specialists is on making sure your loved one gets enough to eat and drink! They understand a healthy diet is likely to improve a person's quality of life. But lay out the risks of not eating and drinking enough, such as higher risks of infection and reduced strength and dehydration. In time, this could speed up their decline.

With that, the message seems to be...

People with Alzheimer's or dementia do not need a special diet - 2018 Alzheimer's Association®

However, some suggest you provide high-calorie meals to make sure your loved one gets enough. Others advise you to provide meals little and often or snacks between meals. It's all a bit confusing, isn't it? While you might have heard that high carbohydrate foods such as bread, rice, pasta, potatoes, sugar etc. increase memory loss.

Clearly, nutrition matters. At this time, your loved one needs a diet and routine as part of their care plan. Your carer should monitor your family member's diet and take note of the symptoms. That way they'll be sure to provide a nutrient-rich diet that your loved one needs.

All in all, it's clear a human diet should consist of fruit and vegetables and meat and fish. Anything else is a recent addition and may not benefit your loved one. Saying that... fruit and vegetables can contain adverse substances so be sure to check out the clean 15 and dirty dozen published by the environmental working group. Also, keep in mind that substances can be stored in animal fat. Therefore, organic produce might be a better option.


Coconut Oil Therapy

Confusion. Struggling with the basics... maths, language... for Steven Newport, an accountant, these were early signs of dementia.

Steve was great with technology. He could take apart and rebuild a computer. But he now found difficulty with a simple calculator. His wife, Dr Mary Newport, a Paediatrician, said: “After a while, he couldn’t even turn one on.”

Steve began to show more signs of early onset dementia in his 50’s. His personality changed and he became distant and developed tremors. After a while, he couldn’t explain what he’d read. Finally, he couldn’t read.

After several failed attempts to enrol Steve in clinical trials, Dr Newport applied once again. Steve was to be screened for the trial but needed to score in the mild-to-moderate range for Alzheimer’s symptoms. Once again, he failed. His symptoms were too severe.

Nevertheless, Dr Newport didn't give up. She found the patent for the treatment which stated coconut oil... MCT (medium chain triglycerides). The very next day, back in May 2005, she began to give Steve tablespoons of coconut oil, which contains 60% MCT's, for breakfast and dinner. Steve's response was dramatic. As the MCT's began to provide ketones, an alternative fuel for his brain, Steve became more alert. He started chatting and finished sentences. Mary said his sense of humour and animation in his face returned. His tremors stopped. And he recognised relatives again.

The day he started coconut oil “a light switch clicked on and the fog lifted”.

The next day, Dr Newport drove Steve back to be tested for the clinical trial once again. He passed. His test score was in the right range to be accepted for the trial.

Dr Newport believed she was on to something, so she continued to feed him coconut oil. In the following weeks and months, he returned to cutting the lawn and helping with housework. He finished projects. Became a hospital volunteer. His normal motion returned and he could read and remember what he read. Coconut oil and MCT's changes their lives for the better.

Now Dr Mary Newport offers a practical guide to using coconut oil and MCT oil with a sensible low-carb diet. Her research into this dietary intervention may benefit others with Alzheimer’s and other neurodegenerative diseases.

With that, Dr Newport suggests dementia patients start with a teaspoon or so of coconut and/or MCT oils and slowly increase to avoid stomach upset or diarrhoea. Then every 2-3 days, increase until the patient is getting between 4-6 tablespoons per day.

As a result, our livers readily convert MCT's into ketone bodies. Unlike longer chains of fats which need digesting before they can pass through our intestines, medium chain triglycerides are easily absorbed into our bloodstream where they then travel to the liver. Notably, Bruce Fife, ND says it has been shown that coconut oil provides a steady flow of ketones while MCT oils peak and drop off.

Due to this newly available energy source for brain cells, research is beginning to show improvement in memory and cognition in over half of the people who take MCT oil.

Dr Newport is consistently receiving reports from caregivers and patients of improvements in daily activities, coordination, returning to hobbies, better sleep, vision and sense of humour. Dr Newport put together a study back in 2010 showing 90% of the participants reported improvements after dietary intervention with MCTs.1

Even though there is not enough evidence to back up claims for medical treatment or a cure, there are studies that show ketone bodies improve cognitive performance. There are "significant differences" in test scores compared to doing nothing at all.2

Coconut oil appears to improve cognitive abilities of Alzheimer’s patients.3

In the end, Steve lost his battle with Alzheimer’s and Lewy body dementia in 2016. Since then, Dr Newport has continued her work to battle dementia.

Notably, other doctors have taken an interest in the power of the coconut. It's worth taking a look at Dr Bruce Fife's Coconut Research Center and a transcript of his Alzheimer’s and dementia summit interview - Coconut Oil Therapy: Fueling Brain Vitality - Why ketones are considered "super fuel" for the brain.


Aromatherapy & Massage

Smell has an impact. A perfume.. a scent creates a chemical reaction in our bodies. So would it be too far fetched to believe aromatherapy might benefit your loved one? In fact, there is some evidence that aromatherapy may be effective to help relax people with dementia. While certain oils may improve cognitive function in Alzheimer's patients.

According to the Alzheimer's society, to improve cognition and mood of Alzheimer's patients, research has recognised lemon balm (Melissa officinalis) treatment to have potential benefits. Whereas, lavender oil can reduce dementia patient's aggressive behaviour incidents.

However, currently, there is not enough evidence to declare whether or not aromatherapy is beneficial.

Massage

As stated by the Alzheimer's society, only a small amount of evidence supports massage to be an effective treatment. So far, massage may help to manage dementia symptoms, such as anxiety, agitation and depression. Even though massage therapies are encouraging, to date studies have not been rigorous enough. Therefore, solid evidence hasn't been provided and further research is required.

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